Categories
Pharmacology

What to monitor

Please,
list four anti-fungal and antiviral medications Indications
Mechanism of action
What to monitor
Patient variables
Side effects
Adverse effects
Teaching

Categories
Pharmacology

What rate of infusion would you set in order to achieve a therapeutic plasma level of 2 ug/ml lidocaine, if vd = 25 l & cl = 0.25 l/min?

George Jungle is a 72-year-old man hospitalized in the Male Medical Ward after a recent MI that requires lidocaine to suppress post-MI ventricular arrhythmias, which he has now developed. What rate of infusion would you set in order to achieve a therapeutic plasma level of 2 ug/ml lidocaine, if Vd = 25 L & CL = 0.25 L/min?

Categories
Pharmacology

Isbn-13: 978-3527337668, isbn-10: 3527337660.

Describe the design of one of the COVID-19 vaccines currently on the market or in development. What is the vaccine made of, how it works, and what are the challenges in its manufacturing, storage, and distribution?
You can write it from anywhere i have just attach as one for reference
Textbook: Stefan Behme, Manufacturing of Pharmaceutical Proteins: From Technology to Economy. Wiley-Blackwell; 2 edition (2015). ISBN-13: 978-3527337668, ISBN-10: 3527337660.

Categories
Pharmacology

Wiley-blackwell; 2 edition (2015).

Describe the design of one of the COVID- 19 currently on the market of development. What is that vaccine made of, how it works, and what are the challenges in manufacturing, storage, and distribution?
Textbook: Stefan Behme, Manufacturing of Pharmaceutical Proteins: From Technology to Economy. Wiley-Blackwell; 2 edition (2015). ISBN-13: 978-3527337668, ISBN-10: 3527337660.

Categories
Pharmacology

Significance of the study

Title: Evaluating Pharmaceutical Services During COVID-19 in Saudi Arabia – A Cross Sectional Survey.
Report classification:
1. introduction
2.statement of problem
3.research questions
4.research objectives
5. research approaches
6. significance of the study
7. scope of the study
8. limitation of the study
9. Hypothesis
10. research organization
(2500 words minimum)

Categories
Pharmacology

What was the general study population? (eg, patients 55 years of age or older, medical condition)

Hello, for this assignment all you have to do is basically look at the Phase 2 clinical trial of a drug, then look at its Phase 3 clinical trial and answer some questions about them. No need for in-depth answers. Short answers that are straight to the point will do. The PDFs for the trials are attached. Here are the questions
Describe the study design (eg, dose-escalation, parallel group, crossover, adaptive design, etc)
Was the study multicenter or single center? In which countries were study centers located?
What was the masking design? (eg, single-masked, double-masked, observer-masked, open-label)
What was the general study population? (eg, patients 55 years of age or older, medical condition)
How many patients?
What were the study interventions (ie, what investigational treatments [investigational drugs, biologics, or devices] were administered)?
What was the study duration? When was the primary timepoint?
What was the primary endpoint and key secondary endpoints?
How were the study designs consistent (or not consistent) with their respective phase?
What did you notice about potential strategic changes, similarities, or potential problems between the two trials? (eg, was there any relation/rationale for the differences among them, such as dosing, endpoint, etc.)
Why do you think the company designed these trials? (ie, what might be the impact to the patient? to the company? How/Why?)

Categories
Pharmacology

Initiatives in the kingdom of Saudi ArabiaObjectives

please I need POWERPOINT to cover Medication safety in high-alert situations – Initiatives in the kingdom of Saudi ArabiaObjectives
To define High Alerts situations
To present the Initiatives, regulation, policies, and experiences done in KSA to overcome medication safety events related to High Alerts situations
To outline the key steps in developing improvement strategies
To identify the appropriate resources and skills needed Sharing challenges and lessons learned

Categories
Pharmacology

Click or tap here to enter text.

HTN Lipid Protocol 2
HYPERTENSION PROTOCOL: INITIAL VISIT 1) RATIONALE a) This protocol will assist in the differentiation between essential hypertension and renal artery stenosis to aid in the identification of patients in need of referral to nephrology to prevent further renal damage from an unidentified renal artery stenosis. The design of the protocol for UTI encompasses these principles. 2) SYMPTOMS
a) HYPERTENSION
i) Blood pressure >140/90 mmHg
ii) Other possible subjective symptoms
(1) Headache
(2) Visual changes
(3) Dyspnea
(4) Chest pain
(5) Sensory or motor deficit b) RENAL ARTERY STENOSIS
i) Onset of hypertension age >55 years or <30 years
ii) History of accelerated, malignant, or resistant hypertension
iii) History of unexplained kidney dysfunction
iv) History of multivessel coronary artery disease
v) History of other peripheral vascular disease
vi) Abdominal bruit
vii) Sudden or unexplained recurrent pulmonary edema
viii) Other possible factors
(1) Absence of family history of hypertension
(2) Other bruits
(3) History of acute kidney injury after administration of ACE inhibitor or angiotensin II receptor antagonist (ARB)
3) HISTORY a) Continue with treatment of hypertension but consult supervising physician if patient has: i) History of accelerated, malignant, or resistant hypertension
ii) History of unexplained kidney dysfunction
iii) History of multivessel coronary artery disease
iv) History of other peripheral vascular disease
v) Abdominal bruit
vi) Sudden or unexplained recurrent pulmonary edema
4) PHYSICAL EXAM a) Perform the following examinations: i) Vital Signs (blood pressure, pulse)
ii) Auscultation for bruits (carotid, abdominal, and femoral)
iii) Palpation of thyroid
iv) Cardiac
v) Respiratory
vi) Lower extremities for edema and pulses
vii) Neurological
b) Consult supervising physician if findings of: i) Abdominal bruit
ii) Another bruit
5) LAB TESTS a) Metabolic panel
i) Cholesterol
ii) Blood sugar
iii) Uric acid level
b) Glomerular filtration rate
c) Consult supervising physician if: i) GFR indicates chronic kidney disease (CKD) or renal failure
6) PHARMACOLOGICAL TREATMENT a) List the hypertension drug classifications and examples you would prescribe in order of treatment according to clinical practice guidelineswithout consideration of race or ethnicity:(Provide generic names for examples. Doses are not needed or required.)
Drug Category/ Classification
Example 1
Example 2
Example 3
Example 4
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Click or tap here to enter text.
Citation (Provide (Author, year) and not full reference): Click or tap here to enter text.
b) 1st line pharmacological treatment if warranted in a non-African American patient after a thiazide diuretic has been given and no compelling contraindications/comorbidities are identified: (Choose a generic drug from the drug class you would like to prescribe to either add to existing treatment or replace a thiazide.)
i) Drug: Click or tap here to enter text.
ii) Dose: Click or tap here to enter text.
iii) Route: Click or tap here to enter text.
iv) Frequency: Click or tap here to enter text.
v) Instructions to provide patient: Click or tap here to enter text.
vi) Caution/Precautions: Click or tap here to enter text.
vii) Using a source such as GoodRX, what is an estimated cost of this drug for a 30-day supply? Click or tap here to enter text.
viii) What patient education is needed for this drug?Click or tap here to enter text.
Citation (Provide (Author, year) and not full reference): Click or tap here to enter text.
c) 1st line pharmacological treatment if warranted in an African American patient after a thiazide diuretic has been given and no compelling contraindications/comorbidities are identified: (Choose a generic drug from the drug class you would like to prescribe to either add to existing treatment or replace a thiazide.)
i) Drug: Click or tap here to enter text.
ii) Dose: Click or tap here to enter text.
iii) Route: Click or tap here to enter text.
iv) Frequency: Click or tap here to enter text.
v) Instructions to provide patient: Click or tap here to enter text.
vi) Caution/Precautions: Click or tap here to enter text.
vii) Using a source such as GoodRX, what is an estimated cost of this drug for a 30-day supply? Click or tap here to enter text.
viii) What patient education is needed for this drug?Click or tap here to enter text.
Citation (Provide (Author, year) and not full reference): Click or tap here to enter text.
d) When should ACEIs be used in African Americans according to the course textbook? Include a citation with matching reference in the reference section. i) Click or tap here to enter text.
ii) Click or tap here to enter text.
iii) Click or tap here to enter text.
Citation (Provide (Author, year) and not full reference): Click or tap here to enter text.
e) Prescribe statin therapy according to the prescription table which follows: Complete the following table to indicate which drug at which dose would be used for different intensity statin therapies to treat high low-density lipoprotein (LDL) as noted in the course textbook. Each drug listed in each column should be a different drug with a specific dose or dose rans as indicated in your course textbook.
High-Intensity Therapy
Moderate-Intensity Therapy
Low-Intensity Therapy
Daily dose lowers LDL-C on average by Click or tap here to enter text.
Daily dose lowers LDL-C on average by Click or tap here to enter text.
Daily dose lowers LDL-C on average by
Click or tap here to enter text.
Drug/Dose 1: Click or tap here to enter text.
Drug/Dose 2: Click or tap here to enter text.
Drug/Dose 1: Click or tap here to enter text.
Drug/Dose 2:Click or tap here to enter text.
Drug/Dose 3:Click or tap here to enter text.
Drug/Dose 4:Click or tap here to enter text.
Drug/Dose 5:Click or tap here to enter text.
Drug/Dose 1: Click or tap here to enter text.
Drug/Dose 2:Click or tap here to enter text.
Drug/Dose 3:Click or tap here to enter text.
What patient education is needed when prescribing statins? Consider any patient counseling points and adverse effects they may need to be aware of or report if experienced.
Click or tap here to enter text.
Citation (Provide (Author, year) and not full reference):Click or tap here to enter text.
7) TREATMENT MONITORING a) How long until a follow up appointment should be done with patient? Click or tap here to enter text.
b) Monitoring needs for blood pressure medication prescribed: (Include physical assessments as well as lab/diagnostics as applicable. If not applicable, enter N/A to show you find it not applicable.)
i) Physical Assessments:
Click or tap here to enter text.
ii) Labs/Diagnostics: Click or tap here to enter text.
Citation (Provide (Author, year) and not full reference): Click or tap here to enter text.
c) Monitoring needs for statin medication prescribed: (Include physical assessments as well as lab/diagnostics as applicable. If not applicable, enter N/A to show you find it not applicable.)
i) Physical Assessments:
Click or tap here to enter text.
ii) Labs/Diagnostics: Click or tap here to enter text.
Citation (Provide (Author, year) and not full reference): Click or tap here to enter text.
8) TREATMENT FAILURE a) How will you know if the treatment is not working or needs to progress? Include a citation with matching reference in the reference section. Click or tap here to enter text.
Citation (Provide (Author, year) and not full reference): References

Categories
Pharmacology

Multiple Sclerosis

Hello, this is a pharmacology project about “Multiple Sclerosis”
It’s going to be 3 pages (title page and reference not included in the 3 pages)
For part two of the 10% of the grade, I will have you do the second option: “create a PowerPoint displaying pictures of assigned organ 6 labeled parts. include pictures of assigned drugs’ mechanism of action and how it affects the organ.
I uploaded a google doc it explains everything.
Thanks in advance

Categories
Pharmacology

Proposal title: Colstrdium difficile infection in hospital and its relation with hospital efficacy and its effect on patient’s length of stay .

Proposal title: Colstrdium difficile infection in hospital and its relation with hospital efficacy and its effect on patient’s length of stay .